Job description
Position Overview
Natera is building a category-defining Health Systems business that moves beyond the transactional “vendor” model into a true strategic partner for leading health systems. We aim to deeply integrate into EMRs, clinical decision support tools, research pipelines, and quality improvement programs — delivering population-scale precision medicine solutions that combine genomics, clinical data, and informatics.
The Head of Product Management, Health Systems will be the senior-most product leader in this business. This role demands a rare blend of technical and commercial expertise — someone who can walk into a CIO’s office, collaborate with an informatics team on HL7/FHIR data integrations, and then pivot to shaping a commercial value proposition for the C-suite. The ideal candidate has hands-on experience building and scaling clinico-genomic data platforms and working with large, complex real-world datasets in healthcare.
This leader will define, build, and launch a portfolio of software-enabled diagnostics, EMR-integrated services, and data-driven clinical tools that differentiate Natera as the health system partner of choice. They will work cross-functionally with engineering, medical, informatics, sales, and research teams — and directly with partner health systems — to make population-level genomic insights actionable at the point of care.
Key Responsibilities
Product Strategy & Vision
Translate the GM’s strategic vision into a cohesive, executable roadmap for Health Systems offerings, encompassing diagnostics, data services, EMR-integrated tools, and decision support.
Identify and prioritize opportunities to embed Natera into health system infrastructure, including:
- EMR integration (Epic, Cerner, etc.)
- Clinical decision support deployments
- Large-scale clinico-genomic databases for quality metrics and value-based care programs
- Biobanking and informatics partnerships
Build a defensible “moat” by creating solutions that are sticky, interoperable, and aligned with health system strategic goals.
Product Development & Execution
- Oversee full product lifecycle: concept → development → launch → scaling → optimization. Additional focus will be on designing and integrating complex data architectures that combine genomics, clinical data, and outcomes.
- Lead cross-disciplinary development teams, ensuring compliance with CLIA/CAP requirements and interoperability standards (HL7, FHIR).
- Ensure solutions address both technical feasibility (data flows, integration wiring, informatics infrastructure) and commercial viability (business models, ROI).
- Troubleshoot in-market adoption barriers and continuously improve product-market fit.
Market Engagement & Customer Integration
Serve as the primary product interface for key customer stakeholders:
- Precision medicine program leaders
- Health IT and informatics departments
- Health system executives (CIO, CMIO, CTO, CEO/COO)
Partner with clinical, research, and informatics leaders to design pilots, research collaborations, and integration roadmaps.
Understand and navigate the informatics decision-making chain within large health systems.
Leadership & Team Building
- Hire, mentor, and grow a team of product managers with deep expertise in diagnostics, software, and health systems.
- Foster a metrics-driven, innovative product culture that thrives in a “big startup” environment — fast-moving, resourceful, and execution-focused.
- Collaborate closely with internal sales, business development, and marketing to ensure consistent messaging, positioning, and enablement.
Business & Commercial Planning
- Build business cases and define success metrics for new initiatives.
- Shape go-to-market strategy in partnership with sales and marketing.
- Lead due diligence for partnerships, licensing deals, and health system agreements.
Qualifications
10+ years in product management/product development in diagnostics, health tech, or medical software — with at least 7 years leading product teams.
Direct experience building and managing large clinico-genomic databases or equivalent real-world data platforms.
Strong background in bioinformatics, computational biology, data science, and engineering — with technical fluency to guide architecture decisions.
Proven success in launching diagnostic or software products into clinical settings with EMR integration and decision support.
Deep understanding of:
- Genomics and clinical data interoperability
- EMR systems (Epic, Cerner)
- Healthcare system workflows
- CLIA/CAP design control requirements
Experience in population health, value-based care models, and enterprise health system contracting.
Commercial acumen — able to translate technical capabilities into health system business value.
Personal Characteristics
- Equal parts technical translator and business strategist.
- Comfortable in C-suite settings and in technical deep-dives with informatics teams.
- Hands-on leader who thrives in ambiguous, high-growth environments.
- Customer-obsessed, collaborative, and outcomes-driven.
- Strong communicator and relationship builder.
Why This Role Is Unique
- Greenfield opportunity to shape how genomic and clinical data is integrated at scale in U.S. health systems.
- Direct impact on Natera’s ability to shift from vendor to embedded partner in population health.
- High visibility and cross-functional influence across engineering, medical, informatics, sales, and executive leadership.
The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.
San Carlos, CA
$1—$1 USD
The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.
Remote USA
$228,300—$285,400 USD
OUR OPPORTUNITY
Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.
WHAT WE OFFER
Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!
For more information, visit www.natera.com.
Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.
All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.
If you are based in California, we encourage you to read this important information for California residents.
Link: https://www.natera.com/notice-of-data-collection-california-residents/
Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.
For more information:
- BBB announcement on job scams
- FBI Cyber Crime resource page
