Job description
About Us
DELFI Diagnostics, Inc. (DELFI Diagnostics) is developing next-generation, blood-based tests that are reliable, accessible and deliver a new way to help detect cancer. Employing advanced machine-learning methods to whole-genome sequencing data, the DELFI (“DNA EvaLuation of Fragments for early Interception”) platform is built to address the highest-burden health challenges. DELFI Diagnostics prioritizes solutions that have the potential to save lives on a global scale, including for historically underserved populations. DELFI Diagnostics’ platform relies on fragmentomics – the discovery that cancer cells are more chaotic than normal cells and, when they die, leave behind tell-tale patterns and characteristics of cell-free DNA (cfDNA) fragments. FirstLook Lung, for individuals eligible for lung cancer screening, is DELFI Diagnostics’ first laboratory-developed screening test and can be part of routine blood work. FirstLook Lung uses millions of data points to reliably identify individuals who may have cancer detected through low-dose CT, including early stage disease with a negative predictive value of 99.8 percent. This test has not been cleared or approved by the FDA.
In our passionate pursuit to radically improve health outcomes, we serve humanity when we:
Lead with Science, Anchor in Pragmatism: We pioneer life-changing science by ensuring quality, transparency, and rigor at all times. We explore thoughtfully, experiment smartly, and deliver impact with conviction.
Build With & For All: We embrace diverse backgrounds to innovate and achieve together. We are not just building a product - we aim to disrupt the path of cancer for all - no matter geography or socioeconomic class
Put We over I: We are a home for high-performing people. Through teamwork, we build collective intelligence. Each of us wins when those we serve and those who serve with us–win. We show up with empathy, humility, and integrity at every step of the journey.
DELFI has 1-2 designated in-office working days each week for employees who live within within 50 miles of Palo Alto CA or Baltimore MD offices
DELFI Diagnostics is seeking an experienced Vice President of Medical Affairs to lead its medical affairs function. This senior leader will oversee the strategic direction and execution of medical affairs initiatives that align with the company’s innovative screening platform. This Medical Affairs leader will play a critical role in driving DELFI’s medical and clinical objectives across multiple functions, collaborating closely with commercial, clinical development, regulatory, research and advocacy. The position requires a visionary leader and skilled operator who can integrate scientific expertise and strategic insights to develop strong relationships with internal and external stakeholders, ensuring that DELFI’s medical affairs activities are aligned with the company’s broader strategy.
What you’ll do
Leadership and Strategy Development
- Lead and develop the Medical Sciences Liaison team, creating a culture focused on scientific excellence and customer-centered solutions
- Implement and enhance the comprehensive medical affairs strategy to address both the clinical interests and needs of key stakeholders, both internal and external to DELFI
- Provide meaningful input to DELFI’s portfolio strategy and long term plan by translating technology and product strengths to unmet medical needs with high clinical utility for DELFI’s approach
- Develop timelines, budgets, and resource plans for key medical affairs initiatives including KOL engagement, guideline oriented evidence and communication planning, medical education programs, and investigator led studies. Ensure that these initiatives are efficiently executed and aligned with corporate milestones
Cross-Functional Collaboration
- Partner with and provide clinical insights to the commercial, clinical development, research and regulatory teams to drive the company’s key objectives
- Create and foster close working relationships with advocacy groups, healthcare providers, and policymakers to support DELFI’s mission and unique clinical and testing platform proposition
Scientific and Clinical Expertise
- Work closely with Clinical Development and Medical Evidence teams to generate high-quality clinical data and evidence, including real-world data that support DELFI Diagnostics’ products and technologies
- Work with the Clinical Development leadership to ensure all clinical studies are designed to generate evidence that informs regulatory submissions, reimbursement strategies, and market access
- Provide clinical guidance on the interpretation of clinical data and ensure the translation of scientific findings into meaningful insights that support the company’s objectives
- Develop and implement strategy for investigator initiated research employing DELFI technology
Clinical Content and Communications
- Operationally oversee the creation, review, and approval process for all medical content, ensuring it meets scientific, regulatory, and legal standards. This includes everything from promotional materials to scientific publications and educational content
- Be accountable for clinical content in all promotional and educational materials and related activities, ensuring scientific integrity and alignment with regulatory standards
- Serve as the primary clinical lead for all external interactions, including with commercial teams, advocacy groups, and government stakeholders
- Contribute to the development of communication and messaging strategies for clinical products, ensuring that the company’s clinical assets are effectively represented
- Position KOLs (Key Opinion Leaders) for presentations at scientific forums, including national and regional specialty society meetings, grand rounds, and continuing medical education (CME) events at targeted institutions
- Identify and execute strategies and tactics for engagement with key influencers in the medical and advocacy communities, ensuring strong relationships and alignment with the company’s goals
Strategic Initiatives and Demonstration Efforts
- Drive the implementation of multi-party demonstration efforts, aligning with company objectives and supporting evidence-based initiatives
- Develop and monitor key performance indicators (KPIs) to measure the effectiveness of medical affairs initiatives and ensure that the goals are being met on schedule, which includes managing operational challenges and ensuring that projects stay on track
What you’ll bring to DELFI
- M.D. or D.O. (Doctor of Osteopathy)
- Minimum of 12 years of experience in medical affairs, with at least 5 years in a leadership role within a biotechnology, diagnostics, or pharmaceutical company
- Proven track record of leading cross-functional teams, integrating scientific data into commercial, regulatory, and strategic objectives
- Extensive experience in creating and overseeing clinical content for both promotional and educational materials
- Experience leading clinical interactions with key stakeholders, including commercial teams, advocacy groups, and government agencies
- Expertise in managing multiple projects, from concept to execution, ensuring timelines, budgets, and quality standards are met
- Strong experience working with advocacy groups, government affairs, and external stakeholders to shape scientific policy and business strategies
- Exceptional leadership, communication, and interpersonal skills, with the ability to engage with both scientific and non-scientific audiences
- Strong ability to navigate complex and fast-paced environments and drive results across multiple organizational functions
What we offer full time employees
- 100% paid medical, dental and vision premiums for employees and dependents
- 16 weeks paid parental leave
- Flexible Time Off
- 5 day winter break in December
- A meaningful mission and strong company cultureThe total compensation for this role includes salary, bonus, equity, and benefits. Actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skillset, years & depth of experience, certifications & relevant education, geography.
$330,000 - $387,000 a year
The total compensation for this role includes salary, bonus, equity, and benefits. Actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skillset, years & depth of experience, certifications & relevant education, geography.
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
This position is not eligible for agency partnership. Resumes and outreach from staffing representatives will be declined.
