Job description
About Us
DELFI Diagnostics, Inc. (DELFI Diagnostics) is developing next-generation, blood-based tests that are reliable, accessible and deliver a new way to help detect cancer. Employing advanced machine-learning methods to whole-genome sequencing data, the DELFI (“DNA EvaLuation of Fragments for early Interception”) platform is built to address the highest-burden health challenges. DELFI Diagnostics prioritizes solutions that have the potential to save lives on a global scale, including for historically underserved populations. DELFI Diagnostics’ platform relies on fragmentomics – the discovery that cancer cells are more chaotic than normal cells and, when they die, leave behind tell-tale patterns and characteristics of cell-free DNA (cfDNA) fragments. FirstLook Lung, for individuals eligible for lung cancer screening, is DELFI Diagnostics’ first laboratory-developed screening test and can be part of routine blood work. FirstLook Lung uses millions of data points to reliably identify individuals who may have cancer detected through low-dose CT, including early stage disease with a negative predictive value of 99.8 percent. This test has not been cleared or approved by the FDA.
In our passionate pursuit to radically improve health outcomes, we serve humanity when we:
Lead with Science, Anchor in Pragmatism: We pioneer life-changing science by ensuring quality, transparency, and rigor at all times. We explore thoughtfully, experiment smartly, and deliver impact with conviction.
Build With & For All: We embrace diverse backgrounds to innovate and achieve together. We are not just building a product - we aim to disrupt the path of cancer for all - no matter geography or socioeconomic class
Put We over I: We are a home for high-performing people. Through teamwork, we build collective intelligence. Each of us wins when those we serve and those who serve with us–win. We show up with empathy, humility, and integrity at every step of the journey.
DELFI has 1-2 designated in-office working days each week for employees who live within within 50 miles of Palo Alto CA or Baltimore MD offices
About Us
Our mission is to cure cancer through high performance, accessible early cancer detection. That means saving lives.
Delfi Diagnostics is a Johns Hopkins spinoff focused on the non-invasive detection of cancer at earlier stages, when it is most curable. DELFI uses artificial intelligence and whole genome sequencing to detect unique patterns of DNA fragmentation in the blood of patients with cancer. These analyses are performed through simultaneous examination of millions of DNA sequences using machine learning to identify tumor-specific abnormalities.
In our passionate pursuit to radically improve health outcomes, we serve humanity when we:
Lead with Science, Anchor in Pragmatism: We pioneer life-changing science by ensuring quality, transparency, and rigor at all times. We explore thoughtfully, experiment smartly, and deliver impact with conviction.
Build With & For All: We embrace diverse backgrounds to innovate and achieve together. We are not just building a product - we aim to disrupt the path of cancer for all - no matter geography or socioeconomic class
Put We over I: We are a home for high-performing people. Through teamwork, we build collective intelligence. Each of us wins when those we serve and those who serve with us–win. We show up with empathy, humility, and integrity at every step of the journey.
Delfi’s Covid-19 Vaccination Mandate: Delfi Diagnostics requires that all employees and contingent workers be fully vaccinated for Covid-19. Proof of vaccination or sincerely held religious belief and/or medical exemption is required upon hire. Delfi Diagnostics will engage in an interactive dialogue process with individuals who have documented medical conditions and/or sincerely held religious beliefs that would prevent them from getting vaccinated, in accordance with all applicable laws.
About the Role
As a Medical Director I, you will work collaboratively, both internally and externally, to develop, implement, and oversee DELFI clinical trials and research collaborations. You will be responsible for driving the scientific planning, strategy, and clinical management of multiple external research collaborations and clinical trials from early development through publication. This role will work extensively internally with clinical development, include medical oversight of trials, and work collaboratively with study investigators and external advisors. You will be responsible for executing medical monitoring activities of DELFI clinical trials, providing both strategic and specific advice to DELFI Clinical Operations team and sites throughout the life of DELFI studies. You will also assist other DELFI cross-functional teams with medical issues/questions related to early phase studies.
What You’ll Do
- Serve as expert clinical contributor within company regarding clinical use and enhancements of current and potential Delfi technologies
- Responsible for the clinical and scientific execution of clinical protocol(s) in DELFI sponsored trials and research collaborations
- Contribute to the protocol, monitoring plan, and CRF development for DELFI sponsored clinical trials by working collaboratively with Clinical Operations, Clinical Data Management, Statistical Science, and Regulatory groups at DELFI.
- Answer medical (protocol) questions directly from sites or from the site manager
- Answer specific inclusion/exclusion criteria questions
- Respond to safety questions and protocol deviations from the site or local IRB
- Attend, participate, and/or present investigator meetings
- Establish and maintain relationships with key academic and community-based clinical institutions, physician and clinical trial site investigators, and third party vendors, in furtherance of clinical evaluation of Delfi technologies
- Regularly organize and attend investigator meetings to enhance awareness and enrollment of studies evaluating DELFI technology
- Regularly engage expert advisors on matters of study design and endpoints
- Ensure execution of clinical trials in support of DELFI’s clinical evidence strategy.
- Provide project team training on disease and/or therapeutic areas
What You’ll Have Accomplished 12 Months From Now
- Supported the execution of pivotal clinical trials and research collaborations that support the development of the DELFI liquid biopsy approach for the non-invasive detection of cancer
- Supported the achievement of key product corporate goals at Delfi Diagnostics
What You’ll Bring to DELFI
- Medical Degree (M.D. or D.O.) with 2+ years of experience in clinical development
- Prior medical practice and fully trained in all aspects of clinical trials
- Clinical data review experience
- Thorough knowledge of the investigational product(s), the protocol, applicable SOPs, GCP, data privacy laws, and local regulatory requirements
Preferred
- Industry experience within pharmaceutical or diagnostic medical device field
- Subspecialty training in Oncology, Pathology, Radiology, or Pulmonology
$190,000 - $230,000 a year
The total compensation for this role includes salary, bonus, equity, and benefits. Actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skillset, years & depth of experience, certifications & relevant education, geography.
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
This position is not eligible for agency partnership. Resumes and outreach from staffing representatives will be declined.
