BridgeBio

We founded BridgeBio in 2014 to develop and deliver medicines for genetic diseases and cancers with clear genetic drivers. Currently, over 10,000 conditions caused by single genetic mutations affect millions of people, yet fewer than 50 FDA-approved therapies exist. We are working to change this.

Our approach uses scientific advancements in genome sequencing, molecular biology, electronic medical records, and patient registries to develop medicines that target diseases at their source. We discover novel genetic disease targets, create specific therapies, test them through global clinical development, and deliver products to patients. This includes treatments like acoramidis (Attruby), BBP-418, skeletal dysplasia, and antibody therapeutics.

We operate with a decentralized model, using a network of affiliate companies. This allows us to advance multiple therapies simultaneously by sharing central resources while individual teams focus on specific diseases. This helps us develop drugs faster.

Our mission is to discover, create, test, and deliver effective medicines to treat patients who suffer from genetic diseases. We operate based on these core values:

• Put patients first: We bridge the gap between business case and scientific possibility for patients with unmet needs.
• Think independently: We encourage rigorous, first-principles thinking.
• Be radically transparent: We consider and test all ideas openly.
• Every minute counts: We use our decentralized model with focused teams to speed up treatment delivery.
• Let science speak: Objective scientific criteria drive our program decisions.

BridgeBio has 201-500 employees. The company looks for skilled individuals who are passionate about creating life-changing medicines, are hands-on, and pursue new solutions.

The work environment is fast-paced and globally minded. The company values cross-functional collaboration, leadership in change, integrity, proactive problem-solving, strong communication, and continuous improvement. It promotes mentorship, collaboration, and career development.

BridgeBio uses a decentralized corporate model and offers a hybrid work model. Roles are based in San Francisco, Palo Alto, Zug, and remote U.S.

We offer competitive pay, including base salary, an annual bonus, and company equity. Our 401K plan includes a 100% employer match on the first 3% and 50% on the next 2%, plus an employee stock purchase program.

For health, we cover 100% of healthcare premiums for employees and their dependents. We also provide mental health support through Spring Health, offering 6 therapy and 6 coaching sessions.

We provide unlimited flexible paid time off and paid parental leave (4 months for birthing parents, 2 months for non-birthing parents). Additional benefits include flexible spending accounts, group term life and disability insurance, and pre-tax commuter benefits. For in-office days, we offer subsidized lunch via Forkable.

We support career development and internal mobility with regular feedback, continuous education, and professional development programs. These include resources like LinkedIn Learning, LifeLabs, Spring Health, and BetterUp Coaching. Employees can also earn recognition and growth through performance-based rewards and our peer-to-peer recognition system. Our referral program awards $2,500 for hired referrals.

We operate on a hybrid work model, giving employees autonomy over their work location and methods.