Job description
Kyverna Therapeutics is a patient-centered, clinical-stage biopharmaceutical company developing cell therapies for patients suffering from autoimmune diseases. Guided by our core values, Stay True to Why, Collaborate to Accelerate, Lead with Clarity, Boldly Innovative, and Own the Outcome, we are committed to transforming the future of treatment for autoimmune disease. Join us at the forefront of cell therapy innovation and help redefine what’s possible.
Position Overview
Kyverna is seeking a Senior Director, Market Access, Health Economics, Outcomes Research (HEOR) & Value to lead the global HEOR and value strategy across the portfolio, spanning early development through commercialization. This role is accountable for defining and delivering evidence strategies that clearly articulate the clinical, economic, and humanistic value of Kyverna’s therapies to payers, HTA bodies, regulators, providers, and internal stakeholders. This role will serve as a senior cross-functional leader and strategic partner to Medical Affairs, Market Access, Commercial, Clinical Development, Regulatory, and Patient Advocacy teams.
This is a highly visible, business-critical role responsible for building scalable HEOR capabilities, shaping access and reimbursement strategies, and ensuring Kyverna’s value story is grounded in robust evidence and aligned with evolving global payer and HTA expectations.
Responsibilities
- Lead the global HEOR and value strategy across pipeline and commercial assets, ensuring alignment with overall corporate, clinical, and access objectives.
- Develop and execute integrated evidence generation plans, including economic models, real-world evidence, patient-reported outcomes, and burden-of-disease studies to support pricing, reimbursement, and access decisions.
- Oversee the design, development, and maintenance of global value dossiers, HTA submissions, payer value narratives, and supporting materials across key markets.
- Partner closely with Clinical Development to embed HEOR endpoints and evidence requirements into clinical trial design and lifecycle planning.
- Collaborate with Market Access and Commercial leadership to support pricing strategy, payer engagement, launch readiness, and post-launch optimization.
- Serve as a senior internal advisor and escalation point on payer, HTA, and value-related questions, translating complex evidence into clear strategic recommendations.
- Build, lead, and mentor a high-performing HEOR and value team, including internal staff and external vendors, consultants, and academic partners.
- Ensure all HEOR activities are conducted in compliance with applicable regulations, industry standards, and internal governance frameworks.
- Monitor evolving global payer, HTA, and policy landscapes to proactively adapt evidence strategies and inform long-term planning.
Qualifications
- Bachelor’s degree required. Advanced degree (MBA, PhD, PharmD, or equivalent) preferred.
- ·Experience in specialty or rare disease sales leadership within the biotechnology or pharmaceutical industry, with a proven record of building and scaling sales organizations in pre-launch and launch settings required.
- 12+ years experience in HEOR, market access, or value strategy within biopharma or biotech, with demonstrated leadership at a senior or executive level.
- Deep understanding of global payer and HTA requirements, including experience supporting submissions and engagements in the US and key ex-US markets.
- Proven track record of developing and executing evidence generation strategies across clinical development and commercialization.
- Strong cross-functional leadership skills with the ability to influence and align senior stakeholders across the organization.
- Experience in rare disease, autoimmune disease, cell therapy, or specialty therapeutics strongly preferred.
- Excellent strategic thinking, communication, and executive presence, with the ability to clearly articulate value to both scientific and non-scientific audiences.
- Successful candidates will bring strong executive presence, strategic judgment, and the ability to operate effectively in a fast-moving, high-growth environment. This role requires exceptional communication skills, a collaborative mindset, and the ability to balance high-level strategy with hands-on leadership.
- Comfort navigating ambiguity and contributing at the executive leadership level is essential.
The national salary range for this position is $280,000 to $305,000 USD annually. The final compensation will be based on individual qualifications, experience, skills, internal equity, and market alignment. This position is also eligible for an annual bonus, comprehensive benefits, and participation in the Company’s stock option plan.
