Apogee Therapeutics

We are a clinical-stage biotechnology company developing biologics for immunological and inflammatory disorders. Our work focuses on conditions like atopic dermatitis (AD), chronic obstructive pulmonary disease (COPD), asthma, and eosinophilic esophagitis, among other inflammatory and immune (I&I) diseases.

Our pipeline includes novel antibody therapeutics. ZUMILOKIBART (APG777), which targets IL-13, is one of our key programs. It is currently in Phase 2 for Atopic Dermatitis, has completed Phase 1 for Asthma, and is in Phase 1 for Eosinophilic Esophagitis. Another program, APG279, targets IL-13 + OX40L and is in Phase 1 for Atopic Dermatitis. We were founded in 2022.

We aim to improve the standard of care for people with inflammatory and immune diseases by developing therapies that offer extended efficacy. We are committed to patients and caregivers by creating distinct treatments.

Our CORE values are Caring, Original, Resilient, and Egoless. We engineer and optimize antibodies to potentially reduce how often injections are needed, aiming to improve patients’ daily lives.

Our team consists of experienced leaders in clinical and commercial development, drug developers, scientists, physicians, and operators. We foster an environment of psychological safety, encouraging team members to share ideas openly.

We operate in a fast-paced, high-growth, and dynamic biotechnology environment. Collaboration is essential, with teams working across functions like IT, Legal, Biometrics, Clinical, and Regulatory Affairs. Some roles are remote-friendly, requiring travel for in-person all-hands meetings. Our culture also values excellence, customer service, quality, and continuous improvement.

We offer a market-competitive compensation and benefits package, including base salary, performance bonuses, and equity grant opportunities. Employees receive health, welfare, and retirement benefits.

We provide three weeks of paid time off (PTO) annually, plus two one-week company-wide shutdowns each year, and dedicated paid sick leave. We support professional growth with access to development resources. We hold regular all-team, in-person meetings to help build relationships and solve problems. We participate in E-Verify for I-9 verification of work authorization in the US and are an Equal Opportunity employer.