Job Description
About Us
We are developing potentially best in class therapies for patients living with severe autoimmune diseases. Our lead antibody, claseprubart (DNTH103), is purposefully engineered with extended half-life, improved potency, and high selectivity for only the active C1s complement protein that drives disease pathology – enabling less frequent and more convenient self-administered subcutaneous injections. Our second clinical candidate, DNTH212 is a first and potentially best in class, bifunctional inhibitor that targets clinically validated and complementary disease modifying mechanisms, Type 1 IFN suppression and B cell modulation – enabling potential for improved clinical outcomes and patient friendly convenient, self-administered subcutaneous injections. To learn more, please visit www.dianthustx.com and follow us on LinkedIn.
About the Role
As the Head of Global Medical Affairs you will play a critical role in shaping and executing the medical strategy across our pipeline, including two pivotal Phase III global programs.
Ideally, you will bring deep expertise in rare diseases and autoimmunology, a strong track record of leadership in medical affairs, and a passion for advancing transformative therapies for patients with high unmet medical needs. Day to day you will work across functions aligning with our Clinical Development teams to support current and future clinical programs as we approach commercialization.
This is an exciting opportunity to lead a high-impact medical affairs function at a pivotal stage of growth, shaping strategy from late-stage development through commercialization.
We are building a culture of individuals who hold our core principles at the center of our operations, with the goal to elevate the care of our patients’ lives. We are open to you working remotely.
Key Responsibilities
- Strategic Leadership:
- Develop and execute the global medical affairs strategy aligned with corporate and clinical development goals.
- Serve as a key member of the executive leadership team, contributing to overall corporate strategy and decision-making.
- Medical Affairs Execution:
- Lead the development of scientific communication plans, medical education, and publication strategies.
- Oversee global KOL engagement, advisory boards, and congress planning.
- Ensure timely and effective support for clinical development, regulatory submissions, and commercial launch readiness.
- Cross-Functional Collaboration:
- Partner closely with Clinical Development, Regulatory Affairs, Commercial, and Market Access teams.
- Provide medical insights to inform lifecycle management, label expansion, and post-marketing commitments.
- Team Building & Leadership:
- Build and lead a high-performing global medical affairs team.
- Foster a culture of scientific excellence, compliance, and patient-centricity.
- Compliance & Governance:
- Ensure all medical affairs activities are conducted in accordance with applicable laws, regulations, and industry standards.
Experience
- MD, PhD, or PharmD required; MD preferred.
- Minimum 15 years of experience in the biopharmaceutical industry, with at least 8 years in medical affairs leadership roles.
- Proven experience supporting global Phase III programs and product launches.
- Deep therapeutic expertise in rare diseases and/or autoimmunology is essential.
- Demonstrated ability to build and scale medical affairs functions in a fast-paced, innovative environment.
- Strong leadership, communication, and stakeholder management skills.
- Global experience and ability to operate effectively across geographies and cultures.
