Head of Commercial Enablement

Job description

Who we are

REGENXBIO is an exceptional place to work. You’ll have the opportunity to collaborate with some of the best and the brightest people, touch amazing science, and be a part of extraordinary plans. Our core values: Trust, Accountability, Perseverance, and Innovation drive everything we do. We aim to bring these values to life every day with all that we do, and we believe that what we do matters - to patients, to their families, and to their communities.

The opportunity

As Head of Commercial Enablement, you will lead the strategy, design, and execution of field operations and commercial enablement to ensure launch readiness, operational excellence, and sustained market performance. Youโ€™ll oversee commercial supply chain planning, CRM and field technology platforms, training and incentive programs, and performance analytics to drive field effectiveness and customer engagement. Partnering cross-functionally across Commercial, Operations, Supply Chain, Finance, and Medical Affairs, this role ensures seamless alignment from demand forecasting to field execution.

What you’ll be doing

  • Oversee commercial supply chain planning and execution, ensuring product availability and timely distribution to meet launch and market demand.
  • Design and implement the commercial field operations model; including sales force structure, territory alignment, call planning, and performance management.
  • Develop and manage the field incentive compensation plan, ensuring alignment with business priorities and compliance.
  • Lead the development and execution of training strategies across sales, market access, and customer-facing teams, with a focus on launch readiness, clinical messaging, and selling excellence.
  • Own CRM (e.g., Veeva), field reporting tools, and enablement platforms, ensuring optimal configuration and user adoption.
  • Serve as the commercial business lead in cross-functional planning forums, ensuring field strategies are aligned with supply and distribution plans.
  • Serve as the liaison between Commercial, CMC, and Operations to align demand forecasting, inventory management, and channel distribution strategies.
  • Develop and implement order-to-cash processes in collaboration with Finance, Quality, and 3PL partners.
  • Manage logistics vendors, distribution networks, and specialty pharmacy relationships to support commercial readiness.
  • Support the establishment and monitoring of KPIs for product delivery, cold chain compliance, and customer service metrics.
  • Lead the implementation, optimization, and adoption of CRM platforms and field productivity tools (e.g., Veeva, Salesforce).
  • Define field KPIs and reporting structures to track performance and inform decision-making.
  • Collaborate with IT and Data teams to ensure seamless integration of commercial tech stack.
  • Develop real-time dashboards, KPIs, and business insights to support field effectiveness and coaching.
  • Lead regular field team performance reviews in partnership with Commercial and Sales leadership.
  • Own field communications strategy to ensure consistent messaging and feedback flow.
  • Lead cross-functional readiness efforts for launch, including alignment across Sales, Market Access, Supply Chain, Finance, Regulatory, and Medical Affairs.
  • Establish launch execution dashboards and readiness checklists to track field and supply pre- and post-launch capabilities.
  • Coordinate internal and external readiness reviews with executive leadership and operational teams.
  • Develop commercial performance dashboards and field insights reports that support decision-making and strategic agility.
  • Translate data into actionable insights for sales management and executive leadership.
  • It is imperative that REGENXBIO employees embody our core values by working collaboratively, building strong relationships and using clear communication to meet shared objectives.

What we’re looking for

  • Bachelorโ€™s degree required; advanced degree (MBA, PharmD, MS) preferred.
  • Minimum of 15 years of experience in biotech/pharma, including leadership roles in commercial operations, field enablement, and/or supply chain logistics.
  • Proven track record of building field infrastructure and operational models to support new product launches.
  • Experience with commercial supply chain operations, including 3PL partnerships, specialty distribution, and demand planning.
  • Deep expertise in CRM systems (Veeva or Salesforce preferred), incentive compensation design, and field reporting tools.
  • Strong understanding of U.S. commercial models, specialty product distribution, and launch best practices.
  • Comfortable in fast-paced, ambiguous environments with the ability to prioritize and drive results.
  • Excellent analytical, communication, and problem-solving skills.
  • Strong project management acumen with attention to detail and deadlines.
  • Experience in gene therapy, retinal diseases, or rare diseases strongly preferred.

Why should you apply?

By joining REGENXBIO, you will have the opportunity to be a part of a growing company, with an incredible team, who is passionate about developing novel AAV gene therapies for patients in need.

We offer a comprehensive and competitive benefit & compensation package which includes market-competitive salaries, an annual bonus program, education assistance, retirement plan with employer match, stock options at all levels, summer hours and more!

In addition, professional development is important to us. ย By joining our team, youโ€™ll have the opportunity to be exposed to challenging projects and have access to development resources to help you grow personally and professionally.

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