Job Description
About Us
We are developing potentially best-in-class therapies for patients living with severe autoimmune diseases. Our lead antibody, claseprubart (DNTH103), is purposefully engineered with extended half-life, improved potency, and high selectivity for only the active C1s complement protein that drives disease pathology – enabling less frequent and more convenient self-administered subcutaneous injections. Our second clinical candidate, DNTH212 is a first and potentially best in class, bifunctional inhibitor that targets clinically validated and complementary disease modifying mechanisms, Type 1 IFN suppression and B cell modulation – enabling potential for improved clinical outcomes and patient friendly convenient, self-administered subcutaneous injections. Our newest candidate, DNTH312, is an internally developed, investigational, first-in-class, next-generation bifunctional fusion protein combining claseprubart and TACI to target potent inhibition of aC1s and BAFF/APRIL. DNTH312 aims to be Phase 1 ready by year end 2027. To learn more, please visit www.dianthustx.com and follow us on LinkedIn.
About the Role
Dianthus Therapeutics is seeking a Senior Medical Science Liaison (MSL) to support the advancement of our neuromuscular disease portfolio, including myasthenia gravis (MG), chronic inflammatory demyelinating polyneuropathy (CIDP), and multifocal motor neuropathy (MMN). This field-based role will build strategic relationships with key opinion leaders, investigators, healthcare professionals, and advocacy organizations while serving as a scientific expert and trusted partner. The Senior MSL will generate actionable insights, support clinical development and evidence generation activities, and contribute to future launch readiness efforts across the portfolio.
We are building a culture of individuals who hold our core principles at the center of our operations, with the goal to elevate the care of our patients’ lives. We are open to you working remotely.
Key Responsibilities
- Serve as the scientific expert for Dianthus’ neuromuscular disease programs and maintain strong relationships with key external stakeholders.
- Conduct compliant scientific exchange regarding disease state education, clinical data, unmet needs, and investigational therapies.
- Gather and communicate medical insights to inform Medical Affairs, Clinical Development, and future commercialization strategies.
- Support clinical trials through investigator engagement, site identification, enrollment support, and protocol discussions as requested.
- Represent Dianthus at scientific congresses, advisory boards, investigator meetings, and other external medical forums.
- Contribute to evidence generation, scientific communications, publications, and educational initiatives.
- Collaborate cross-functionally with Medical Affairs, Clinical Development, Clinical Operations, Regulatory Affairs, Market Access, and Commercial teams.
- Ensure all activities are conducted in compliance with applicable regulatory, legal, and company requirements.
Experience
- Advanced scientific or clinical degree required (PharmD, PhD, MD, DO, or equivalent).
- 7+ years of pharmaceutical or biotechnology industry experience, including significant field medical experience.
- Previous experience in neurology or immunology/inflammation is preferred.
- Experience building relationships with neuromuscular, neurology, rare disease, or immunology thought leaders and investigators.
- Strong understanding of clinical research, evidence generation, and scientific communications.
- Excellent communication, presentation, and influencing skills.
- Ability to work independently in a fast-paced, highly collaborative environment.
- Willingness to travel extensively within the assigned territory.
