Job Description
Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X.
About This Role
Axsome Therapeutics is seeking a Director, Market Access Deal Analytics to serve as a strategic leader in developing data-driven solutions that inform payer strategy, reimbursement optimization, pricing, and patient access. The ideal candidate will bring deep experience in payor and PBM deal analytics, strong understanding of payor incentives, Medicare and Medicaid reimbursement, understanding of specialty pharmacy, hub, patient services programs, and a pragmatic, action-oriented mindset that connects insights to execution. This position reports to the Senior Director, Pricing and Contracting Strategy.
This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles.
Job Responsibilities and Duties include, but are not limited to, the following:
Conduct robust analytics to support business cases to be presented to Pricing Terms Committee (PTC)
Support development on contracting language that supports meeting of business intent
Lead analytics strategy to inform payer contracting, coverage optimization, and payer engagement across Axsome’s in-line and pipeline products
Conduct claims data analyses [rejections, reversals, abandonment] to understand coverage dynamics, formulary behavior, and their implications on uptake and persistency
Design modeling frameworks to guide formulary negotiations, segmentation strategies, and gross-to-net (GTN) investment optimization
Build predictive tools to estimate how payer policies and pricing dynamics influence new therapy adoption across CNS specialties
Drive integration of payer analytics into National Account pull-through strategy, including actionable field-level insights for Market Access and Field Sales teams
Support development of key metrics, and report payer and PBM contract performance to Pricing Committee and Executive Leadership
Construct scenario-based forecasting models that simulate the impact of price and access changes on revenue and patient access
Monitor formulary positions and their downstream impact on prescribing behavior, conversions, and persistency to inform contract renewal cycles
Partner with Finance and GTN teams to continuously refine accruals based on evolving pricing and access dynamics
Collaborate closely with Forecasting, Commercial Operations, HEOR, and Market Access Data Science teams to harmonize analytics across functions
Embed analytics into pricing and access strategy development, ensuring that all recommendations are grounded in data and aligned to business goals
Proactively identify opportunities to improve data infrastructure, automate insight generation, and enhance decision support capabilities
Requirements / Qualifications
Bachelor’s degree in Economics, Statistics, Public Health, or related field. Advanced degree (MBA, MPH, PhD) preferred
Minimum 10 years in pharmaceutical or healthcare analytics with a focus on market access, pricing, or payer strategy
Proven track record in supporting product launches from an access analytics perspective
Strong background in CNS therapeutic areas or other specialty/rare disease domains, highly preferred
Ability to work on site Monday, Tuesday & Thursday
Experience, Knowledge and Skills
In-depth understanding of U.S. payer systems (commercial, Medicare, Medicaid), reimbursement pathways, and formulary dynamics
Proficiency in large-scale healthcare datasets (claims, syndicated data sources, longitudinal data sources)
Strong experience in payer contracting analytics, GTN modeling, and assessing ROI on market access investments
Expertise in PBM/Payor Contract Language
Familiarity with data visualization platforms (e.g., Power BI, Tableau) and cloud-based data ecosystems
Ability to develop and validate predictive models using machine learning or regression-based techniques
Ability to influence senior stakeholders across Commercial, Access, and Corporate functions
Experience managing external vendors, data partners, and cross-functional projects with multiple competing priorities
Excellent communicator who can distill technical content into strategic narratives
Salary and Benefits:
The anticipated salary range for this role is $190,000 - $215,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package.
Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law.
Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration.
