Personalis, Inc.

Founded in 2011 in Fremont, California, we are a biotechnology research company working to improve cancer treatment through personalized testing. We develop sensitive assays that combine tumor and normal profiling with our algorithms. These assays provide advanced insights into how cancer evolves, helping to detect minimal residual disease (MRD) and recurrence early. They also aid in selecting targeted therapies through comprehensive genomic profiling and improving biomarker strategies for drug development.

Our oncology portfolio includes products like the NeXT Personal MRD ctDNA assay and other cell-free DNA (cfDNA) platforms. We use advanced ctDNA technologies for sensitive detection and to gain cancer insights, supporting molecular residual disease analysis and therapy selection. Our work also involves technologies such as NGS, Immuno-oncology, Tumor Profiling, Tumor/Normal Analysis, Immunogenomics, Personalized Cancer Vaccines, Immune Modulators, Tumor Escape, Tumor Microenvironment, HLA Typing, Neoantigens, Whole Exome, Whole Transcriptome, Machine Learning, and Neural Networks.

We serve pharmaceutical companies, biotechnology firms, hospitals, and clinicians, assisting them with treatment management and therapeutic selection. Our operations include informatics for clinical diagnostics, laboratory work, and data-driven technology solutions, such as LIMS and clinical data platforms. We also handle commercial analytics, global event management, medical science liaison activities, sales training, and client experience management for clinical diagnostic communications.

We are a company of 201-500 employees. Our work environment is fast-paced and high-growth, operating in a regulated healthcare diagnostics field. We prioritize cross-functional collaboration and strive for engineering excellence through mentorship, strong code quality, automation, and strict adherence to regulatory standards.

We offer a comprehensive benefits package:

• Medical, dental, and vision insurance
• 401(k) retirement match program
• Employee Stock Purchase Plan (ESPP)
• Tuition reimbursement
• Sick and vacation time
• Commuter benefits and EV charging stations
• Onsite gym and wellness benefits

Our compensation packages generally include an annual performance-based bonus (or sales incentive plan) and long-term incentive units (equity).